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Delivery was really fast. I got my order much sooner than expected.
Product Usage: This product is intended for research purposes only.
All product information available on this website is for educational purposes only. Any form of bodily introduction into humans or animals is strictly prohibited by law. This product should only be handled by licensed and qualified professionals. It is not a drug, food, or cosmetic, and must not be misbranded, misused, or mislabeled as such.
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BPC-157 with Arginine Salt
BPC-157 is a synthetic 15-amino-acid pentadecapeptide derived from the gastric mucosal protein BPC.
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BPC-157 is a synthetic 15-amino-acid pentadecapeptide derived from the gastric mucosal protein BPC. In vitro studies document interactions with VEGFR2, EGFR, and FAK phosphorylation cascades, with modulation of pro-angiogenic signalling networks. Preclinical in vivo models have examined its effects on nitric oxide synthase activity, extracellular matrix protein expression, and actin cytoskeletal dynamics in connective tissue contexts.
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3D Molecular Structure
Drag to rotate · scroll to zoomBPC-157 with Arginine Salt5mg 1 vial | 5mg 10 vials | 10mg 1 vial | 10mg 10 vials
| Chemical Formula | C68H112N20O24 |
|---|---|
| Synonyms | Body Protection Compound-157, Bepecin, PL 14736 |
| Molar Mass | 1,419.5 g/mol |
| CAS Number | 137525-51-0 |
| PubChem CID | 175763564 |
| Total Compound Content | 5 mg per vial |
| Shelf Life | 36 months |
BPC-157 is a synthetic pentadecapeptide (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) identified as a partial sequence of the gastric cytoprotective protein BPC. In cell-based assays, BPC-157 potentiates VEGFR2 phosphorylation and downstream ERK1/2 activation, implicating modulation of pro-angiogenic signalling axes. Additional in vitro data indicate upregulation of focal adhesion kinase (FAK) activity and actin cytoskeletal reorganisation, consistent with observed effects on cell migration in scratch-wound models. In preclinical in vivo studies, administration is associated with eNOS expression upregulation, collagen fibril remodelling, and fibroblast proliferation responses — processes of interest across connective tissue biology, angiogenesis research, and extracellular matrix remodelling models. The peptide exhibits stability across physiological pH and is supplied lyophilised for laboratory reconstitution. Independently third-party HPLC-tested; COA available per batch.
Results refer to the tested sample. Check the batch and date in the report.
Why does BPC-157 demonstrate greater stability than many peptide-based research compounds?
BPC-157 contains multiple proline-rich motifs that are believed to contribute to resistance against enzymatic degradation under a range of experimental conditions. This structural characteristic distinguishes it from many peptide-based research compounds and has contributed to interest in its biochemical stability, peptide persistence, and signaling activity in mechanistic investigations.
What is the relationship between BPC-157 and VEGFR2/FAK signaling pathways?
Experimental investigations have reported enhanced VEGFR2 phosphorylation together with increased focal adhesion kinase (FAK) activity and downstream ERK1/2 signaling. These observations have positioned BPC-157 as a useful research tool for studying angiogenic signaling networks, cellular migration processes, cytoskeletal organization, and extracellular matrix-associated pathway regulation.
How does BPC-157 differ from TB-500 in mechanistic research?
BPC-157 and TB-500 are frequently compared because they influence distinct signaling networks. Research involving BPC-157 has focused primarily on VEGFR2, FAK, ERK1/2, eNOS, and extracellular matrix-associated pathways, whereas TB-500 investigations emphasize actin dynamics, cytoskeletal organization, cell migration, and tissue remodeling mechanisms.
Their differing mechanistic profiles make them valuable tools for comparative studies of peptide-mediated signaling and cellular regulatory processes.
Customer Reviews (10)
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5 / 5
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Verified Buyer
Always impressed with the speedy shipping and high quality of the items.
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Verified Buyer
Great experience with the support team and purity exceeded my expectations. Our research results have been outstanding. Five stars all around.
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Verified Buyer
Top-notch quality from the prompt communication, quality was great and dispatch was incredibly fast. Highly satisfy and will return. The experimental results were exceptional.
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Verified Buyer
We got fantastic research results. Extremely pleased with the fast turnaround times, purity exceeded my expectations. Thanks for the outstanding support!
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Verified Buyer
Highly satisfied with the prompt communication, happy with the quality of this compound. Highly recommend this vendor. My test results are great.
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Verified Buyer
Great experience with the super fast shipping, purity exceeded my expectations. My laboratory research results exceeded expectations. Will buy again.
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Verified Buyer
Definitely the best source for this stuff hands down! Very happy with the quality and delivery times.
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Verified Buyer
Great products. Will be reordering next week.
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Verified Buyer
Nice site, fast shipping, superb quality. My new vendor for sure!
